University of East Anglia

Fully funded PhD Studentship
A Short & Flexible Total Synthesis of 20S Proteasome Inhibitors
School of Chemical Sciences and Pharmacy
This fully funded studentship is available to start in October 2009, under the supervision of Prof Phil Page, in the internationally recognised School of Chemical Sciences and Pharmacy, UEA Norwich (RAE 5). The project is funded by the School of Chemical Sciences and Pharmacy.
UK/EU APPLICANTS ONLY ARE ELIGIBLE FOR THIS FUNDING (this is because of the eligibility rules of the funding body)
Project description:
FUNDING IS AVAILABLE FOR UK/EU STUDENTS. FUNDING FOR THIS PROJECT WILL COVER TUITION FEES AND STIPEND FOR UK STUDENTS, EU STUDENTS WILL NORMALLY BE ELIGIBLE FOR TUITION FEES ONLY. INTERNATIONAL STUDENTS WILL NOT BE ELIGIBLE FOR THIS FUNDING; THEY ARE STILL WELCOME TO APPLY FOR THIS PROJECT BUT WOULD HAVE TO FIND ALTERNATIVE FUNDING. The aim of this project is to establish a rapid and efficient total synthesis of the proteolytic enzyme inhibitors lactacystin, PS-519, the core structure of KSM-2690 B1 and (+)-oxazolomycin A, salinosporamides A and B, and cinnabaramides A-G. The project will capitalize on significant advances made in our group toward the challenging highly substituted core; the synthesis is designed to provide access to novel intermediates and derivatives important for structure-activity studies.
Contact:
For informal enquiries about this position please contact Prof Phil Page at p.page@uea.ac.uk or the Faculty of Science Admissions Office at scipg@uea.ac.uk or +44 (0) 1603 593002.
How to apply:
An application can be downloaded from our website at http://www1.uea.ac.uk/cm/home/services/units/mac/aao/courses/PG. Completed application forms should be submitted to the Admissions Office, Faculty of Science, University of East Anglia, Norwich, NR4 7TJ.
The deadline for receipt of completed applications is Friday 13th March 2009.